GLOSSARY OF TERMS

Anandamide | Anandamide, also known as N-arachidonoylethanolamine or AEA, is an endogenous cannabinoid neurotransmitter. The name is taken from the Sanskrit word ananda, which means “joy, bliss, delight”, and amide.

Bioavailability | Subcategory of absorption; the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. By definition, when a medication is administered intravenously, its bioavailability is 100%.

Cannabinoid | Class of diverse chemical compounds that act on cannabinoid receptors on cells that repress neurotransmitter release in the brain. The most well-known cannabinoids include THC, CBD, CBN and THCa.

Dosage | The size or frequency of a dose of a medicine or drug.

Endocannabinoid System | a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis.

Extraction | a separation process consisting in the separation of a substance from a matrix. In cannabis processing, this is the process of pulling essential oils, cannabinoids and Terpenes from cannabis material.

First-pass Metabolism | The phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation. It is the fraction of lost drug during the process of absorption, which is generally related to the liver and gut wall.

Indica | The Indica strains originated from a higher altitude and can be found predominantly in countries known for their hash culture such as Morocco, Afghanistan, Nepal and Turkey. These plants are shorter and fuller plants compared to their sativa counterparts. Indicas are known for providing strong analgesic effects.

Nutraceutical | a portmanteau of the words “nutrition” and “pharmaceutical”, was coined in 1989 . The term is applied to products that range from isolated nutrients, dietary supplements and herbal products, specific diets and processed foods such as cereals, soups, and beverages designed to provide health benefits.

Pharmaceutical Grade | The US Pharmacopeia (USP) publishes official monographs for certain substances. These monographs include specific assay methods and product specifications to assure identity and potency. Material that is tested by these methods to meet those specifications is then eligible to be called pharmaceutical grade, or USP. Standards for assessing cannabis ingredients and production are limited at this time, so individual organizations strive to ensure that their ingredients and production processes meet the standards of other industries.

Sativa | Sativa strains originated in an area around the equator and can be found in countries like Colombia, Mexico, Thailand and several African Nations. Sativas are generally known for producing more mental, energetic effects than indicas.

Terpene | the pungent oils that give cannabis varieties their distinctive properties, aromas and flavors.

Topical | relating or applied directly to a part of the body.

Transdermal | a route of administration wherein active ingredients are delivered across the skin for systemic distribution.

Vaporizer | a device that generates a particular substance in the form of vapor, especially for medicinal inhalation.